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Premarin Vaginal Cream and/or Equivalents

Drug Related Drug Names
Premarin Vaginal Cream 0.625mg/g and/or Equivalents Premarin Vaginal Cream

Premarin Vaginal Cream (conjugated estrogens)

Premarin Vaginal Cream Description

Developed by Wyeth – Ayerst, Premarin vaginal cream is a clinically proven therapy that is a low dose option for treating menopausal changes in the vagina. These changes can create troublesome symptoms such as painful sex and vaginal dryness. This medication treats the basic cause of these signs and restores vaginal tissues by providing lubrication and elasticity during its usage. Premarin is used for treating kraurosis vulvae, dyspareunia and atrophic vaginitis. It basically helps to stimulate cell development and growth and to improve ephithelial thickness of vaginal mucosa. Intravaginal creams help to produce high levels of blood estrogen when compared to oral doses.

Every gram of vaginal cream (white) comprises of 0.625 mg of conjugated estrogens that come in a nonliquefying cream base. 42.5-gram tubes are available in the market along with a calibrated plastic applicator. The non medicinal ingredients in the cream include white wax, purified water, sodium lauryl sulfate, propylene glycol monostearate, phenylethyl alcohol, mineral oil light, methyl stearate, glyceryl monostearate, glycerin and cetyl esters wax.

Conditions treated by Premarin Vaginal Cream

Premarin is basically a mixture of estrogen hormones that are used for treating menopausal symptoms like irritation, burning, vaginal dryness and hot flashes. Some of the other uses of this cream include preventing osteoporosis in women who are in the post menopausal stage and for replacing estrogen in those women who have an ovarian failure or experience other conditions causing a natural lack of estrogen in their bodies. Sometimes, Premarin is also used to partially treat cancer in men and women. Any kind of vaginal discomfort or painful sex problems is controlled to a large extent with the use of this cream.

Estrogen is a sex hormone (female) that ovaries produce. This hormone is needed for several processes in your body. Lack of production of estrogen can create a lot of havoc in your body including emotional or psychological troubles besides physical problems. In such cases, dementia or heart disease can strike postmenopausal women but this medication should not be used to treat these conditions. As a matter of fact, the drug increases risk of developing such conditions.

Premarin Vaginal Cream Dosage Information

a.) Typical Dosage Recommendations

The medication is usually administered cyclically but for short-term usage only. Using the drug for a long period of time will develop adverse effects in the user. To treat atrophic vaginitis, mucosa should initially be conditioned with oral therapy (short course). Vaginal treatment should be commenced with lowest possible dosage. Dose adjustment depends upon the degree of atrophy. Premarin is usually taken topically or intravaginally. 2 mg to 4 mg of the drug is taken depending upon your condition’s severity. Premarin should be taken every day. A typical Premarin cycle is 25 days followed by 5 days.

b.) Missing a Dose

Take the missed dose as soon as you remember that you have missed it. If it is time for your next dose; do not take the missed one. Taking extra doses to catch up may prove harmful.

c.) Overdosing

If you think you have used a lot of medication, get emergency medical attention. Symptoms of overdosing can include vaginal bleeding, vomiting and nausea.

Premarin Vaginal Cream Warnings

While using this medication, it is better to avoid smoking because risks, associated with heart attack, stroke or blood clots caused by this medication, increase. To make sure that this drug does not cause any unpleasant effects, you have to get your blood tested on a periodic basis. Thyroid function will also have to be tested. If you are to undergo any surgery, inform your surgeon well ahead of time. You may be expected to discontinue the medication for a short period of time. Premarin can affect the results of specific tests. You should not use the drug if you have a history of the following ailments: blood clot, stroke, heart attack (or a history), abnormal vaginal bleeding, liver disease and uterine, breast or hormone related cancer.

The drug can increase risks of endometrial hyperplasia (can lead to uterine cancer). Taking Premarin for an extended period of time can increase risks of developing blood clots or stroke. The drug can cause congenital defects when taken by a pregnant woman. An effective kind of birth control must be used while using Premarin. Breastfeeding mothers should also not take this medication since the ingredients in the drug can pass through breast milk to the new born. The drug has all possibilities to slow down milk production in breastfeeding mothers. People below 18 years of age should not be administered the drug without consulting a doctor.

Premarin Vaginal Cream Side Effects

An allergic reaction to Premarin vaginal cream includes:

With the onset of these side effects, you need to consult your doctor.

Some of the serious side effects can include:

The other side effects include:

Less serious problems include:

Possible Drug Interactions With Premarin Vaginal Cream

When you are prescribed Premarin, make sure you inform your doctor if you take any of the following medications:

  • Coumadin(warfarin)
  • Synthroid(levothyroxine)
  • diabetes medicine or insulin taken orally
  • Rifater (rifampin, isoniazid and pyrazinamide)
  • Nizoral (ketoconazole)
  • Mysoline (primidone)
  • Tegretol (carbamazepine)
  • Dilantin (phenytoin)
  • Few other drugs that can interact with Premarin include:

    If you have any questions about buying discount Premarin Vaginal Cream online or any other prescription products you can contact our team of professional Patient Service Representatives or one of our pharmacists 24-7 by calling 1-800-226-3784.

    Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.