Motilium and/or Equivalents
|Drug||Related Drug Names|
|Motilium 10mg and/or Equivalents||Domperidone|
Developed by Janssen Pharmaceuticals, domperidone is an antidopaminergic drug known by several trade names. Motilium is one such trade name and can be used orally, intravenously or rectally for suppressing vomiting and nausea. Lactation can also be stimulated with the use of this drug. Certain medical problems can affect the usage of Motilium. Therefore, it is important to inform your doctor in such cases and more so when you have bleeding from your stomach or problems with bowels, pituitary tumor, liver disease or basic medication sensitivity to domperidone.
Make sure you store the medicine out of reach of children. Keep it away from heat and light and places that are damp such as bathrooms, kitchen sink etc. Moisture and heat can make the medicine break down.
Conditions Treated By Motilium
Motilium or domperidone is a dopamine antagonist that blocks dopamine receptors present in the upper part of your gastrointestinal system. These receptors in the upper end of the digestive system tighten the muscles present in the stomach’s entrance and relax those that are present in the stomach’s exit. Contractions in the stomach muscles are also caused as a result. This helps to pass food faster through your stomach and facilitates to prevent nausea and vomiting as well as other problems associated with the stomach. In short, Motilium is used for delayed gastric emptying with dyspepsia or gastro esophageal reflux.
The drug also helps to treat vomiting and nausea along with uncomfortable bloating of stomach plus a feeling of fullness in your stomach. Reflux is also treated through the use of Motilium. The medication is also used for stimulating lactation. It is used as an antiemetic in patients who receive radiation and cytostatic therapy. The medication facilitates examination (radiological) of the upper gastro intestinal tract. The drug has been found effective in treating gastroparesis which is a stomach motility condition. The drug does not cross blood brain barrier like metocloparamide and therefore can be administered on patients with Parkinson’s disease. It also helps to treat pediatric gastro esophageal reflux or vomiting in infants.
Motilium Dosage Information
a.) Typical Dosage Recommendations
Dosage to be followed will be different for different individuals. For treating upper gastrointestinal motility disorders, the recommended dosage in adults is an oral dose of 10 mg to be taken 3 to 4 times every day at least 15 to 30 minutes before meals. The drug can be taken at bedtime if required. In more severe cases, the dose is also increased to 20 mg taken 3 or 4 times every day.
For treating vomiting and nausea that is associated with Dopamine Agonist Antiparkinsonian Agents, the recommended dosage in adults is an oral dose of 20 mg taken 3 to 4 times every day. For achieving symptom control, higher doses could be required while titration of the drug is happening.
b.) Missing a Dose
If you have missed a dose of Motilium, take it whenever you remember. However, if it is time for your next dose, skip the missed one. Do not take extra doses to make up for the skipped ones.
Overdosing of Motilium demands emergency medical attention or contacting the Poison Helpline. Some common symptoms of Motilium overdosing can include loss of muscle control or balance, lightheadedness, irregular heartbeats, dizziness, disorientation and difficulties in speaking.
Motilium should not be used wherever gastrointestinal stimulation could be dangerous. Mechanical perforation or obstruction and gastrointestinal hemorrhage are typical conditions. This is also the case with patients with a prolactin – releasing pituitary tumor. Although no studies have effectively proved the effects of Motilium on unborn babies, pregnant women are to take this drug only when the possible benefits outweigh the potential hazard, if any. The ingredient used in Motilium excretes in very low proportion through breast milk. Breastfeeding mothers are not usually recommended to take the drug during this period.
Efficacy and safety of the drug has not been determined in children and therefore, the drug is not to be administered to children. The drug can result in gynecomastia or galactorrhea which demands stopping the drug as quickly as possible. Many of the side effects caused by this medication are because of dosage and therefore when dosage is lowered, most of these serious symptoms are either alleviated or minimized to a large extent. Patients with hepatic impairment should exercise caution when taking this drug.
Motilium Side Effects
Side effects are prone to occur in many drugs that have a lot of benefits to offer. There are some side effects an individual can experience while consuming this medication and these include some common as well as rare symptoms such as swelling of mouth, face, feet, lower legs or hands, racing pulse or heartbeat and pounding, irregular and fast heart rate. There are some side effects that can arise and disappear during the course of treatment. These show up because the body will need to adjust to the medication. However, when side effects are bothersome, you might consider checking with your doctor.
Some of these side effects include:
- menstrual irregularities
- swelling of eyes
- redness and pain in the skin
- hot flashes
- hives and dryness of mouth
Some of the rare symptoms include:
- stomach cramps
- nervousness and mental dullness
Other signs include:
- leg cramps
- lack of strength
- speaking difficulties
- painful urination
- constipation and change in appetite
Very high blood pressure can occur in patients who have certain kinds of tumors in the adrenal glands.
Drug Interactions With Motilium
When you are prescribed Motilium, you have to inform your doctor if you are taking or planning to take anticholinergic drugs. This is because the latter can nullify the benefits offered by Motilium. The active ingredient in Motilium enhances small intestinal and gastric motility and therefore, accelerates drug absorption from your small bowel but slowing down drug absorption from the stomach. This makes enteric coated or sustained release medication interact with Motilium. Care should be exercised when Motilium is administered along with MAO inhibitors.
Tell your doctor about all other medicines you use, especially:
- a Monoamine Oxidase Inhibitor (MAOI):
This is not a complete list of all medications that may interact with Motilium. Please notify all of your health care providers about the prescription and over-the-counter medications you currently take. This should include a complete list of all vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a treatment of a new medicine without properly notifying your primary health care professional or doctor.
If you have any questions about buying discount Motilium online or any other prescription products you can contact our team of professional Patient Service Representatives or one of our pharmacists 24-7 by calling 1-800-226-3784.
Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.