Mirapex and/or Equivalents
|Drug||Related Drug Names|
|Mirapex 0.125mg and/or Equivalents||Mirapex, Pramipexole, Sifrol ER|
|Mirapex 0.25mg and/or Equivalents||Auro-Pramipexole, Mirapex, Pramipexole, Simpral|
|Mirapex 0.5mg and/or Equivalents||Act-Pramipexole, Mirapex, Pramipexole|
|Mirapex 1mg and/or Equivalents||ACT Pramipexole, Mirapex, Pramipexole|
|Mirapex 1.5mg and/or Equivalents||Act-Pramipexole, Mirapex, Pramipexole|
Pramipexole or Mirapex is a non ergoline dopamine agonist that is usually indicated for the treatment of early or initial stage Parkinson’s disease as well as restless legs syndrome. This medication has many of the effects as dopamine, a chemical. This chemical is naturally present in your body. When the levels of dopamine in your brain decline, Parkinson’s disease sets in. Therefore, Mirapex helps to restore the natural balance of dopamine in your brain. Mirapex tablets also treat restless legs syndrome. Mirapex ER or extended release tablets are also available commercially for treating symptoms and signs of both early and advanced Parkinson’s disease.
Mirapex can be used solely or with certain other drugs to treat Parkinson’s disease. This medication is the first agent (Parkinson’s) that is approved by the FDA after Eldepryl, Somerset’s monoamine oxidase inhibitor. Mirapex is manufactured by Pharmacia and Upjohn, Boehringer Ingelheim. The drug will largely improve your ability to bring down shakiness or move. Unsteadiness, slowed movement and stiffness can also be removed. Mirapex should be stored at room temperatures and kept away from heat and moisture.
Conditions Treated By Mirapex
Mirapex or pramipexole dihydrochloride tablets are intended for treating symptoms and signs of idiopathic Parkinson’s disease. These tablets are also used to treat moderate to severe primary restless legs syndrome (RLS). RLS is a condition where the patient has an urge to move legs generally accompanied by or as a result of unpleasant and uncomfortable leg sensations. Such symptoms tend to become worse during inactivity or periods of rest such as sitting or lying. These signs will be partially or entirely relieved by motion such as stretching or walking for as long as the activity prolongs.
There are certain off label uses of Mirapex as well. It is used to treat cluster headache and for counteracting the issues with sexual dysfunction that is experienced by certain users of selective serotonin reuptake inhibitor antidepressants. There have also been pilot studies that are conducted to show the efficacy of Mirapex in treating bipolar disorder. Investigations are also conducted to prove the efficacy of the drug in treating fibromyalgia and clinical depression.
Mirapex Dosage Information
a.) Typical Dosage Recommendations
Dosage of the drug is primarily dependent upon your clinical condition and your response to treatment. It usually takes at least a few weeks for you to observe full effects of this medication on you. Dosage recommendation of Mirapex ER should be made by your doctor only. It is only him who will decide the changes that can or should be made to the dosage of this drug. Generally, Mirapex ER is taken only once in a day. In the initial stages, the starting dosage will be 0.375 mg every day and this dosage is gradually increased. Increase in dosage should not happen more frequently than five or seven days. You should not increase or decrease the amount of consumption without consultation from your doctor. Similarly, medication should not be discontinued without expert and professional approval. The drug can be taken before or after meals. However, you can also take it with food if you experience an upset stomach.
b.) Missing a Dose
If you have missed a dose, take it as soon as you remember it. But if it is time for taking the next subsequent dose, then skip the missed one. Do not take extra doses for compensating missed ones at inappropriate times.
If you suspect an overdose of Mirapex, you have to get emergency medical attention by contacting your local Poison helpline number.
There are good chances of Mirapex impairing your reactions or thinking capacity. Therefore, it is extremely important that you be meticulous while you drive after taking the drug or perform any action that requires you to be alert. Before taking the drug, you should conduct a few tests to check on your blood pressure. Alcohol consumption can enhance the side effects of the drug. Do not get up too quickly from a lying or standing position to avoid feeling dizzy. Function of the kidney declines with age and regular use of Mirapex. Hence, elderly people are more prone to hallucinations and dizziness. If you are pregnant, you should consult your doctor before taking the medication. Lactating mothers can face the problem of Mirapex affecting their nursing infant through milk. Therefore, breastfeeding should be avoided. Stopping the drug should be done only after consultation with your doctor. Stopping abruptly can result in withdrawal reactions in the user.
Mirapex Side Effects
Mirapex should be discontinued if you experience one or more of certain side effects. These include:
- falling asleep all of a sudden immediately after feeling alert
- heavy drowsiness
- dark colored urine
- muscle pain
- shortness of breath
- dry cough
- discomfort in chest
- quick weight loss
- appetite loss
- tiredness or weakness
- uneven heartbeats
- twitching of limbs and face, tremors etc.
Very serious side effects of using this medication are usually not observed. Relatively less serious side effects can include
- thinking problems
- blurred vision
- weight changes or changes in appetite
- mild drowsiness
- spinning sensation
- stomach pain
- dry mouth
- swelling in the limbs
The drug can also impair the systemic regulation of blood pressure with orthostatic hypotension as a result. Patients who use this drug find an impaired ability to respond to a challenge that is orthostatic in nature.
Possible Drug Interactions With Mirapex
Mirapex is known to create a sense of drowsiness and hence certain drugs can add to the sleepiness cause by this medication or turn harmful altogether. Therefore, it is better to stay away from anxiety, seizures and depression medication, muscle relaxers, sleeping pills, narcotic pain medication, sedatives and allergy medicines. If you are making regular use of medications for Parkinson’s disease, inform your doctor accordingly. You should also contact your doctor if you consume:
- Symmetrel (amantadine)
- Tagamet (cimetidine)
- Cadizem (diltiazem)
- Zantac (ranitidine)
- Dyrenium (triamterene)
- medications for preventing and treating vomiting or nausea such as:
- medications for treating psychiatric disorders such as:
If you have any questions about buying discount Mirapex online or any other prescription products you can contact our team of professional Patient Service Representatives or one of our pharmacists 24-7 by calling 1-800-226-3784.
Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.