Mexitil and/or Equivalents
|Drug||Related Drug Names|
|Mexitil 100mg and/or Equivalents||Mexiletine, Novo-Mexiletine|
|Mexitil 200mg and/or Equivalents||Mexiletine, Novo-Mexiletine|
Mexitil Drug Description
The generic name of Mexitil is mexiletine hydrochloride. The IUPAC name of the drug is 1-methyl-2-(2, 6-xylyloxy) ethylamine hydrochloride. It is a white crystalline powder with a slight bitter taste and is readily soluble in water and alcohol. The drug is sold in the form of 150 mg, 200 mg and 250 mg capsules. The non medicinal ingredients consist of colloidal silicon dioxide, magnesium stearate, simethicone, titanium dioxide, corn starch, pharmaceutical glaze, gelatin, FD&C Blue No.1 and FD&C Red No 40. Mexitil 150 mg and 250 mg capsules contain FD&C Red No 28 and FD&C Yellow No 10. The capsules may contain shellac, lecithin, sodium lauryl sulphate and FD&C Blue No 1 Aluminium Lake.
Conditions Treated by Mexitil
Mexitil is primarily used to treat serious cases of irregular heartbeat conditions like ventricular tachycardia. It is an anti-arrhythmic drug, which implies it can restore steady heart rhythm by obstructing the electrical signals in the heart which are responsible for irregular heartbeats. The steady heart beats ensure a regular continuous blood flow preventing the possibility of heart attacks and strokes due to formation of clots in the blood streams. The drug may be prescribed to diabetic patients for alleviating symptoms of neuropathy. Some diabetic patients experience a prickling or burning sensation on the hands and feet. In addition, stabbing pains may occur at night. The condition is called peripheral neuropathy. Mexitil is effective in reducing these uncomfortable sensations.
Mexitil Dosage Information
a.) Typical dosage recommendations
Take Mexitil as recommended by the doctor. The dosage depends upon the age of the patient, the severity of the condition, the body weight and other factors. The capsules are taken orally at fixed times of the day, as directed by the doctor. A patient may be kept under clinical observation while beginning the medication to enable the doctor to monitor the effect of the drug. Do not change the dosage without consulting a doctor. The patient's condition may worsen with irregular usage of the medication.
b.) Missing a dose
Mexitil ought to be taken at appointed times of the day. If you miss a particular dose, you may take a capsule within a short while after the scheduled time. Should you forget a dose altogether, pass over the missed dose and take the subsequent dose at the appointed time. Do not take an additional dose to recompense for the skipped dose.
It is vital that you take Mexitil exactly as asked to, by the doctor. An overdose of the drug can be dangerous or even fatal. Potential effects of an overdose of Mexitil may consist of drowsiness, very low blood pressure, a slow heart rate, confusion, numbness or a tingling sensation on any part of the body. Unfortunate overdose cases may result in coma or death. If you overdose on the medication by accident, look for emergency help immediately. A recent overdose may be rectified by administering activated charcoal.
A patient with a ventricular pacemaker may be administered Mexitil with constant monitoring. Caution should be employed when Mexitil is used for treating patients with intra ventricular defects or sinus node dysfunction. Like most anti-arrhythmic drugs, Mexitil may cause arrhythmias to worsen. It is prudent to exercise caution while prescribing the drug to patients with hypotension (low blood pressure) and congestive heart diseases. The use of Mexitil should be carefully monitored for patients with a history of seizures. As the drug is broken down in the liver, individuals suffering from liver dysfunction should be monitored closely when being treated with Mexitil. Post-marketing studies have revealed reports of unusual results of liver function tests. Adequate studies and research have not yet been carried out to establish the use of the drug Mexitil on pregnant women. Limited studies have shown that the drug does not impair fertility. The effect of the drug on foetal development is not known. A pregnant woman may be treated with Mexitil, if the possible benefits outweigh the potential danger to the foetus. Mexitil passes into human milk in significant concentrations. Nursing mothers should not be administered the medication. If the use of Mexitil is a necessity for the mother, the infant should be administered formula food. Mexitil is not recommended for paediatric use, as safety of the drug for children has not been established. In general, the use of Mexitil should be restricted to patients suffering from acute ventricular arrhythmia.
Mexitil Side Effects
Mexitil may induce several serious side effects. These include a new and possibly worse pattern of heat beat, chest pain or discomfort, wheezing, unexplained bleeding or bruising, recurrent fevers, infections, ulcers inside the mouth an?Pd a sore throat. Stop medication and arrange for a consultation with the doctor immediately. The non medicinal components may cause a sudden allergic reaction, which may be life threatening. Seek emergency medical attention if you perceive swelling of the lips, throat, tongue or any part of your face. Allergic reactions may include rashes on the skin as well.The drug may cause less severe side effects like an upset stomach, loss of appetite, nausea, constipation, heartburn, fatigue, dizziness, headache, depression and a dry feeling inside the mouth. Continue with the drug and talk to your doctor if you experience any of the conditions listed above. A change in the dosage may alleviate the symptoms. The list of side effects is not exhaustive. Other symptoms may occur too.
Mexitil Drug Interactions
When Mexitil is used concurrently with phenytoin, rifampin and phenobarbital, lower levels of Mexitil plasma have been reported. It is advised that Mexitil plasma level be monitored during simultaneous use of Mexitil with the drugs mentioned above to prevent ineffectual therapy with the drug. Simultaneous use of Mexitil and the drug cimetidine has been found to raise or lower the level of Mexitil plasma as well. Hence patients taking both medications at the same time ought to be monitored closely. Mexitil and magnesium aluminium hydroxide to treat acidity may not be used together as the combination is found to lower the level of serum digoxin. It is prudent to inform the doctor of any medication or supplements you might be taking, if you are prescribed Mexitil for your condition.
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Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.