Lysodren and/or Equivalents
|Drug||Related Drug Names|
|Lysodren 500mg and/or Equivalents||Lysodren|
Lysodren is the retail or brand name for mitotane tablets. It is an oral medication used to treat certain types of cancers. In this sense it is a chemotherapeutic agent. The medicine comes in a tablet form that consists of several colorless crystals. It has not taste but has a distinguishing odor of its own. The medicine is normally sold as a 500 mg tablet. The biochemical mechanical action of this drug remains unknown. The drug causes increased hyrocycortisol and helps to reduce corticosteroids in the body. In short it can be described as an adrenal cytoxic agent.
Conditions treated by Lysodren
Lysodren is commonly prescribed for adrenal corical carcinoma. It is used to treat both functional and non functional types of the disease.
Lysodren Dosage Information
a.) Typical dosage recommendations
Typically, doctors suggest 2 to 6 g of the medicin 3-4 times a day. Increased doses may be required at later stages of the treatment. Doctors may reduce the dose or stop treatment if severe side effects occur. In many cases, patients are treated with higher doses or maximum doses up to 16 g. Doctors in this case have to constantly monitor a patient’s reaction to the medication. When patients show any sign of stress the medication is discontinued or lower doses are given. The treatment usually continues untill the patient responds to the medication or until major side effects are observed. However, if no positive change is seen after 3 months of treatment then doctors consider it a failure and might discontinue use of the drug. Positive signs include reduced size of tumors, reduced pain etc.
b.) Missing a dose
Lysodren should be administered under strict and regular supervision. However, if you still miss a dose then you must contact your doctor immediately. Depending on the number of hours you have missed the dose by the doctor will be able to decide what to do.
Doctors usually supervise how a patient reacts to different dosages. They may increase or decrease the medication depending on how well a patient responds to the medication. However, if you feel that you may have overdosed on the medication by having too much it immediate medical help will be required. You may experience extreme nausea, vomiting, stomach ache, or weakness when you overdose on the medication. Hospitalization may be required in extreme cases of an overdose.
Lysodren tablets should be used under strict and regular supervision. Only experienced doctors with several years of expertise in cancer treatment should administer the drug. The drug must be discontinued in event of any shock or trauma faced by patients. This is because it is highly active in adrenal suppressions. Lysodren should be administered only under the doctor’s supervision and advice to patients suffering from severe liver, kidney or heart disease you must inform your doctor. This will help them determine which dose of the drug is ideal for you. Continuous Lysodren medication may result in brain damage. This is a major reason why the drug should be administrered only under strict supervision. Long term use may cause changes in behavior and moods especially in older patients. A significant number of patients suffer from adrenal insufficiency with continuous use of Lysodren. In this case, steroid replacement medication needs to be administered. Patients who have been using Lysodren for a long time are at risk of lethargy. This may affect normal functions like driving, walking, jogging etc. it is therefore advised to take extreme care while carrying out any physical activities, although avoiding them during medication is better. Lysodren should be administered to pregnant women or women who have just given birth to new born babies only if absolultely necessary. Otherwise by and large this medication should be avoided. It is not proven whther Lysodren affects the fetus or how much it affects the fetus, precaution is therefore necessary when administering the drug to women. Women who are presently breastfeeding should avoid the medication until they have stopped breastfeeding. If the drug is absolutely necessary for a new mother then it is advisable to give the new born baby supplements instead of breastfeeding. When the drug is being administered to older patients, it is advisable to start with low dosages then increase the dose gradually depending on the patients reaction to the drug.
Lysodren Side Effects
If you face difficulty in breathing, tightening or swelling of facial muscles, irritation in the tongue or throat then you must immediately seek medical help. You may need to be hospitalized or the doctor may have to lower your dosage. Other common side effects may include feeling faint, change in heartbeat, increased sweating, ticklish feeling under feet and palms, sudden rise in body temperature and chills, blurred vision or confusion. If you have just started taking the drug then you may experience dizziness and drowsiness until your body gets used to the medication. Rapid change in blood pressure is also a common side effect of Lysodren. However if your blood pressure falls too low or climbs too high it is better to discontinue medication or decrease dosage. Gastroinestinal infections, nausea and vomiting are also seen in patients who use Lysodren. The central nervous system may also get affected resulting in vertigo in some cases. If you experience either one or more than one of the symptoms you must immediately contact your doctor.
Lysodren Drug Interactions
Lysodren accelerates the metabolism of Warfarin leading to the need for increased dosages of Warfarin. Lysodren should be given with caution to patients receiving other drugs for hepatic enzyme induction. Lysodren should not be given to patients who have shown hypersensitive reactions to it in the past.
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Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.