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Hyzaar DS and/or Equivalents

Drug Related Drug Names
Hyzaar DS 100mg/25mg and/or Equivalents Cozaar Comp, Hyzaar DS, Losartan/HCTZ

Hyzaar DS (losartan/hydrochlorothiazide)

Hyzaar DS Description

Hyzaar DS is a combination drug and contains losartan potassium and hydrochlorothiazide. It is marketed by Merck & Co.

It is used as a combination therapy for the treatment of hypertension. It is administered only if you are using losartan potassium and hydrochlorothiazide individually and their doses have been stabilized. In case you suffer from certain heart diseases, then it can also help in reducing the possibility of a stroke.

Conditions Treated by Hyzaar DS

Hyzaar DS is used for the treatment of hypertension. It also helps in reducing the chances of a stroke, for certain heart diseases.

It is a combination drug. The losartan potassium is an antagonist of the Angiotensin II receptors, i.e. they prevent the activation of the down-signaling processes initiated by Angiotensin II receptors. This leads to vasodilation and other effects. The combined effect of all these is a decrease in blood pressure. Even though there are other drugs available for treating hypertension, losartan potassium is preferred because they are capable of preventing cardiovascular effects such as strokes at the same time.

Hydrochlorothiazide acts by affecting certain mechanisms in the kidneys. This leads to a decreased reabsorption of sodium ions by the kidneys. This in turn affects the retention of water by the kidneys. Hence, the volume of blood reduces. This leads to a decreased load on the heart.

It can thus be used for the treatment of Hypertension. It is usually used in combination with other drugs. In this case, it is losartan potassium.

Hyzaar DS Dosage Information

Hyzaar DS is sold in the market in the tablet form. It is available in a 100mg /25mg dosage. The 100mg is losartan potassium and 25mg is hydrochlorothiazide. The dosage varies from person to person and it must be titrated for each individual. Only when the medication is well tolerated should the dosage be increased.

a.) Typical Dosage Recommendations

Hyzaar tablets may be started only after the patient has been stabilized on the individual components. Once this is done, the patient is started with an initial dose of 50mg / 12.5mg or 100mg / 25mg. If the patient fails to respond to the higher dose, to, then you can start the double strength medications, i.e. Hyzaar DS 100mg /25mg once a day.

a.) Missing a Dose

If you miss a dose, then you should take the medication immediately on remembering. However, if it is time for your next dose, then you may skip the dose and resume your schedule as normal. DO not overdose to make up for a missed dose.

c.) Overdosing

There is not much data available on the side effects of overdosage of Hyzaar DS. However, if you overdose, then the symptoms should be related to overdosage of losartan potassium and hydrochlorothiazide individually. The common symptoms of overdosage of losartan potassium include hypotension and increase in the heart rate. Hydrochlorothiazide overdosage may cause depletion of electrolytes in the body. This causes reduced sodium, chloride ions in the body. In addition, dehydration may result from excessive urine production.

In case, you overdose, seek medical attention immediately to avoid complications.

Hyzaar DS Warnings

Hyzaar DS is to be strictly avoided during pregnancy. It is an Angiotensin receptor antagonist and can affect the fetus and even cause its death. As soon as a patient gets pregnant, Hyzaar should be discontinued.

The hydrochlorothiazide component of Hyzaar renders it incompatible for people who hane a hypersensitivity to sulfonamide-related drugs.

In some cases, after administration of the first dose, hypotension is known to have occurred. The chances of this occurring are higher if the patient has lost water due to diuretics, diarrhea, vomiting etc.

In some patients, treatment with hydrochlorothiazide may cause Hyperuricemia. It can also lead to the occurrence of gout. In addition, it may also cause an increase in the excretion of magnesium from the body. This leads to decreased levels of magnesium in the body and is called hypomagnesemia. At the same time, they can cause an increase in the levels of glucose and cholesterol levels in the body.

A change in the fluid and electrolyte balance may cause severe conditions of the liver. Hence, this drug is to be used with caution in case of people with impaired liver function. Similarly, it is also not recommended for patients who are suffering from severe renal impairment.

Hyzaar DS Side Effects

Hyzaar DS consists of two drugs both of which are known to cause side effects. The common side effects caused by Hyzaar DS include:

If these symptoms persist for long or become severe, then you must consult with your doctor.

Hyzaar DS can induce a hypersensitive response in certain individuals. The symptoms of a hypersensitive reaction include:

Hyzaar DS can cause the blood pressure to drop drastically causing Hypotension. Hypotension causes light-headedness, fainting etc. It can affect the liver and causes symptoms that include dark/brown urine, vomiting etc. Hyzaar is known to induce the breakdown of muscle tissue. This causes weakness or tenderness of muscles.

These are the severe side effects of Hyzaar DS. If you develop any of these symptoms, then you must discontinue your medication immediately and consult with your doctor. You must seek medical attention immediately.

Possible Drug Interactions with Hyzaar DS

  • NSAIDs (non-steroidal anti-inflammatory drugs):
  • Muscle Relaxants:
  • Narcotic Medication:
    • hydrocodone (Lortab, Vicodin)
    • meperidine (Demerol)
    • methadone (Methadose)
    • oxycodone (OxyContin)
    • propoxyphene (Darvon, Darvocet)
  • Steroid Medication:
  • Deltasone (prednisone)
  • There are many other medications too that can interact with Hyzaar DS. It is very important that you consult with your doctor before starting any new medications, to prevent any complications arising from drug-interactions.

    If you have any questions about buying discount Hyzaar DS online or any other prescription products you can contact our team of professional Patient Service Representatives or one of our pharmacists 24-7 by calling 1-800-226-3784.

    Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

    Hyzaar DS and/or Equivalents warnings, side-effects and general information