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Pantoloc

With all the false advertising you find on the web I was holding my breath ordering from CanadaDrugs.com. My prescription arrived by US Mail in 10 days, was "real" Brand, and cost 50% then here in Florida. I will be refering all of my friends to Canada Drugs. com Thank You, DUANE

D. Nifong

Seminole,

(see Protonix)

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The following monograph is provided by Thomson Healthcare and may be related to the prescription drugs listed above.

Drug monograph for the active ingredient in Pantoloc

The following information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

PANTOPRAZOLE (Systemic)

Some commonly used brand names are:

In the U.S.—

Protonix

In Canada—

Pantoloc

Description

Pantoprazole (pan-TOE-pra-zole) is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat duodenal and gastric ulcers and gastroesophageal reflux disease (GERD), a condition in which the acid in the stomach washes back up into the esophagus.

Pantoprazole works by decreasing the amount of acid produced by the stomach.

This medicine is available only with your doctor's prescription.

Oral

Delayed-release tablets (U.S. and Canada)

Parenteral

Injection (U.S.)

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For pantoprazole, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to pantoprazole. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy— Pantoprazole has not been studied in pregnant women. However, studies in animals have shown that pantoprazole causes problems. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.

Breast-feeding—It is not known whether pantoprazole passes into human breast milk. Since this medicine has been shown to cause unwanted effects in animals, it may be necessary for you to take another medicine or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor.

Children— Studies on this medicine have been done only in adult patients, and there is no specific information comparing the use of pantoprazole in children with use in other age groups.

Older adults—This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking pantoprazole, it is especially important that your doctor and pharmacist know if you are taking any of the following:

Warfarin (e.g., Coumadin)—May increase risk of abnormal bleeding

Other medical problems—The presence of other medical problems may affect the use of pantoprazole. Make sure you tell your doctor if you have any other medical problems, especially:

Liver disease —This condition may cause pantoprazole to build up in the body

Zinc deficiency, or prone to—May make your condition worse.

Proper Use of This Medicine

Take pantoprazole tablets immediately before a meal, preferably in the morning. Pantoprazole tablets may be taken with food or on an empty stomach.

Swallow the tablet whole. Do not crush, break, or chew the tablet.

It may take several days before this medicine begins to relieve stomach pain. To help relieve this pain, antacids may be taken with pantoprazole, unless your doctor has told you not to use them.

Tell your doctor if you have ever had problems with a lack of zinc in your body. Your doctor may have you take zinc supplements.

Take this medicine for the full time of treatment, even if you begin to feel better . Also, keep your appointments with your doctor for check-ups so that your doctor will be better able to tell you when to stop taking this medicine.

Dosing—The dose of pantoprazole will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of pantoprazole. If your dose is different, do not change it unless your doctor tells you to do so.

For oral dosage form (delayed-release tablets):
- To treat gastroesophageal reflux disease (GERD):
  - Adults—40 milligrams (mg) once a day, preferably in the morning for up to eight weeks. Your doctor may advise you to continue taking the medicine for an additional eight weeks if your condition does not improve after the first eight weeks.
  - Children—Use and dose must be determined by your doctor.
- To treat gastric ulcers:
  - Adults—40 mg once a day, preferably in the morning for four weeks.
  - Children—Use and dose must be determined by your doctor.
- To treat duodenal ulcers:
  - Adults—40 mg once a day, preferably in the morning for two weeks.
  - Children—Use and dose must be determined by your doctor.
For injection dosage form:
- To treat GERD:
  - Adults—40 mg injected into a vein once a day for seven to ten days.
  - Children—Use and dose must be determined by your doctor.
For injection dosage form:
- To treat conditions in which the stomach produces too much acid:
  - Adults—80 mg injected into a vein twice a day. Your doctor may adjust your dose.
  - Children—Use and dose must be determined by your doctor.

Missed dose—If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage—To store this medicine:

Keep out of the reach of children.
Store away from heat and direct light.
Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

It is important that your doctor check your progress at regular visits. If your condition does not improve, or if it becomes worse, check with your doctor.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Abdominal or stomach pain; blistering, loosening, peeling, or redness of skin; bull's eye-like rash on skin; changes in facial skin color; chest pain; diarrhea; difficulty in speaking; difficulty in urinating; discoloration, itching, numbness, pain, or redness at place of injection; fast or irregular breathing; increased frequency and volume of urination; infection; large, hive-like swellings on eyelids, face, lips, mouth, and/or tongue; loosening and/or stripping off of top layer of skin; loss of appetite; loss of vision (sudden); nausea; painful urination; pain in joints or muscles; puffiness or swelling of the eyelids or around the eyes; shortness of breath, troubled breathing, tightness in chest, and/or wheezing; skin rash, hives, and itching; skin tenderness with burning; unusual tiredness or weakness; unusual thirst; vomiting; yellow eyes or skin

Incidence not known

Blindness; bloody or cloudy urine; bloody, black or tarry stools; continuing vomiting; dark-colored urine; decreased vision; fever; general feeling of tiredness or weakness; greatly decreased frequency of urination or amount of urine; high fever; light-colored stools; muscle cramps or spasms; muscle pain or stiffness; pale skin; sores, ulcers, or white spots on lips or in mouth; stomach pain; swelling of feet or lower legs; swollen glands; unexplained bleeding or bruising

Get emergency hep immediately if any of the following symptoms of overdose occur

Symptoms of overdose

Abdominal pain; blurred vision; confusion; fast, pounding, or irregular heartbeat or pulse; feeling faint, dizzy, or lightheaded; feeling of warmth or heat; flushing or redness of skin, especially on face and neck; headache; nausea and vomiting; sleepiness or unusual drowsiness; sweating

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.

More common

Headache

Less common or rare

Aching, fullness, or tension in sinuses; anxiety; back pain; belching; blurred vision; chills; confusion; constipation; cough; difficulty in moving; dizziness; drooling; feeling of constant movement of self or surroundings; flatulence; hoarseness; indigestion; loss of energy or strength; migraine headache; muscle rigidness or stiffness; neck pain; pain; rectal problems; ringing or buzzing in the ears; runny or stuffy nose; sensation of spinning; sneezing; sore throat; trouble in sleeping

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Developed: 04/03/2000
Revised: 02/15/2005

The information contained in the Thomson Healthcare products is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare makes no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

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